Topoisomerase I, Mitochondrial (TOP1MT) Antibody MBS4380530 from MyBioSource.com

Product Specs
ItemTopoisomerase I, Mitochondrial (TOP1MT) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS4380530
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ApplicationsImmunohistology (Formalin-Fixed)
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
ReactivityHuman. Others not known
TargetTopoisomerase I, Mitochondrial (TOP1MT)
IsotypeIgG
Molecular Weight70kDa
CloneTOP1MT/2883R
HostRabbit
ImmunogenDNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity
NCBI Full Gene NameDNA topoisomerase I mitochondrial
ClonalityMonoclonal